Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983942 | 0.86 | KDM4E (0.31) | — | |
| SCHEMBL19984025 | 0.84 | MAPK14 (0.32) | — | |
| SCHEMBL19984040 | 0.81 | MTNR1A (0.34) | FGFR1FGFR4 | |
| SCHEMBL16619419 | 0.79 | HTR6 (0.45) | — | |
| SCHEMBL19984031 | 0.77 | ALDH1A1 (0.38) | PDE10AFGFR1FGFR4 | |
| SCHEMBL19983825 | 0.76 | CARM1 (0.32) | — | |
| SCHEMBL19984027 | 0.76 | MAPK14 (0.37) | CYP2D6 | |
| SCHEMBL19984182 | 0.75 | P2RX7 (0.31) | — | |
| SCHEMBL19984299 | 0.73 | SLC6A4 (0.35) | — | |
| SCHEMBL19983978 | 0.73 | MTNR1A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |