Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 4/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | GALR2 | O43603 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | GALR1 | P47211 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.31 |
| ▸ | GAK | O14976 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984027 | 0.94 | MAPK14 (0.37) | FBP1MAPK14GAK | |
| SCHEMBL19983885 | 0.91 | FBP1 (0.39) | ADRB2FBP1MAPK14GALR2NPC1 | |
| SCHEMBL19984022 | 0.89 | AKR1C3 (0.38) | ADRB2MAPK14GAK | |
| SCHEMBL19983907 | 0.88 | FPR1 (0.36) | FBP1MAPK14 | |
| SCHEMBL19984007 | 0.86 | MAT2A (0.34) | NPC1RAB9AP2RX7TRPA1 | |
| SCHEMBL19984182 | 0.86 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL19984154 | 0.84 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL19983791 | 0.84 | KDR (0.33) | ADRB2P2RX7GAK | |
| SCHEMBL19983775 | 0.84 | EGFR (0.34) | FBP1P2RX7 | |
| SCHEMBL19983844 | 0.84 | ALDH1A1 (0.35) | FBP1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |