Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626544 | 0.90 | GPR84 (0.36) | CYP2C9MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL19984013 | 0.79 | HTR2A (0.35) | CYP2C19CYP2C9CYP3A4MEN1KMT2A | |
| SCHEMBL19983894 | 0.76 | GPR84 (0.39) | CYP1A2CYP2C8CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL19983834 | 0.75 | PRKAG1 (0.42) | MEN1KMT2ASMN1; SMN2ACHEPRKAG1 | |
| SCHEMBL19983877 | 0.73 | GPR84 (0.36) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19983764 | 0.72 | APP (0.38) | CYP1A2CYP2C8CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL19983880 | 0.72 | MEN1 (0.36) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19983815 | 0.70 | CYP2C9 (0.43) | CYP2C19CYP2C9CYP3A4MEN1KMT2A | |
| SCHEMBL19984194 | 0.70 | GPR84 (0.39) | CYP1A2CYP2C8CYP2D6CYP2C19KDM4E | |
| SCHEMBL19984147 | 0.68 | CYP2D6 (0.36) | CYP1A2CYP2C8CYP2D6CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |