Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983944 | 0.79 | GPR84 (0.40) | KDM4EALDH1A1HTR1AHTR2AHTT | |
| SCHEMBL19983751 | 0.78 | GPR84 (0.40) | KDM4EALDH1A1HTR1AHTR2AHTT | |
| SCHEMBL19984001 | 0.78 | MAPK8 (0.48) | KDM4EALDH1A1HTR1AHTR2AHTT | |
| SCHEMBL19984005 | 0.78 | HTR2A (0.44) | KDM4EALDH1A1HTR2ACHRNB2CHRNA7 | |
| SCHEMBL19983738 | 0.77 | GPR84 (0.39) | KDM4EALDH1A1HTR1AHTR2AHTT | |
| SCHEMBL19983869 | 0.77 | MMP2 (0.46) | KDM4EALDH1A1HTR1AHTR2AHTR6 | |
| SCHEMBL19983849 | 0.76 | GPR84 (0.40) | HTR1AHTR2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983867 | 0.76 | HTR2C (0.42) | KDM4EALDH1A1HTR1AHTR2ACHRNB2 | |
| SCHEMBL19984197 | 0.76 | GPR84 (0.49) | HTR2ACHRNB2CHRNA7CHRNA4PTGS2 | |
| SCHEMBL19983891 | 0.76 | GPR84 (0.49) | HTR1AHTR2ACHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |