Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626624 | 0.90 | KLKB1 (0.33) | NAMPT | |
| SCHEMBL19984028 | 0.88 | ALDH1A1 (0.37) | CYP11B2CYP11B1NAMPT | |
| SCHEMBL16626783 | 0.88 | P2RX7 (0.35) | SLC6A4SLC6A2KCNH2NAMPTHTR2A | |
| SCHEMBL16626750 | 0.83 | RAB9A (0.36) | NAMPTHTR2C | |
| SCHEMBL19984136 | 0.80 | MEN1 (0.39) | NAMPTHTR2C | |
| SCHEMBL16626644 | 0.79 | CYP11B1 (0.37) | CYP11B2CYP11B1MAT2ANAMPT | |
| SCHEMBL19983950 | 0.79 | CYP11B1 (0.41) | SLC6A4CYP11B2CYP11B1MAT2A | |
| SCHEMBL19984208 | 0.79 | SLC6A4 (0.34) | SLC6A4SLC6A2KCNH2CYP11B2CYP11B1 | |
| SCHEMBL16626401 | 0.79 | SLC6A2 (0.37) | SLC6A4SLC6A2CYP11B2CYP11B1MAOA | |
| SCHEMBL19984214 | 0.79 | MEN1 (0.32) | SLC6A4SLC6A2NAMPTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |
| WO-2015050412-A1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-09 | — | — | WO | disclosed |