Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 6/20 | 0.41 |
| ▸ | MPO | P05164 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984048 | 0.88 | TDO2 (0.42) | TDO2MPOGPR84ALKBH5FTO | |
| SCHEMBL19983943 | 0.81 | CYP3A4 (0.36) | TDO2GPR84SLC6A2SLC6A3TTK | |
| SCHEMBL19984030 | 0.81 | GPR84 (0.48) | MPOGPR84SLC6A2SLC6A3ALKBH5 | |
| SCHEMBL19983836 | 0.79 | SLC6A2 (0.39) | TDO2MPOGPR84SLC6A2SLC6A3 | |
| SCHEMBL31415127 | 0.73 | GPR84 (0.72) | TDO2MPOGPR84ALKBH5FTO | |
| SCHEMBL19984039 | 0.71 | GPR84 (0.50) | MPOGPR84SLC6A2SLC6A3ALKBH5 | |
| SCHEMBL19984043 | 0.71 | — | — | |
| SCHEMBL19983731 | 0.70 | GPR84 (0.37) | TDO2GPR84CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL14036644 | 0.70 | MPO (0.72) | MPOGPR84HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL16618810 | 0.69 | HTR6 (0.41) | SLC6A2SLC6A3TTKCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |