Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 6/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983970 | 0.90 | SLC6A2 (0.38) | SLC6A2SLC6A3SLC6A4GPR84MAPK1 | |
| SCHEMBL19984037 | 0.89 | SLC6A2 (0.34) | SLC6A2SLC6A3SLC6A4KDM4EMEN1 | |
| SCHEMBL19983841 | 0.82 | SLC6A4 (0.43) | SLC6A2SLC6A3SLC6A4HTR2AKCNH2 | |
| SCHEMBL19984030 | 0.82 | GPR84 (0.48) | SLC6A2SLC6A3MPOSLC6A4HTR2A | |
| SCHEMBL19984249 | 0.79 | TDO2 (0.41) | SLC6A2SLC6A3MPOKDM4EHTR2A | |
| SCHEMBL19984003 | 0.70 | GPR84 (0.50) | MPOHTR2AGPR84HTR2C | |
| SCHEMBL19983715 | 0.69 | HTR2A (0.42) | KDM4EHTR2AGPR84 | |
| SCHEMBL19983891 | 0.69 | GPR84 (0.49) | MPOSLC6A4HTR2AGPR84HTR2C | |
| SCHEMBL16626682 | 0.69 | HTR6 (0.33) | SLC6A2SLC6A3KDM4EMEN1GAA | |
| SCHEMBL19983739 | 0.68 | CHRNB2 (0.50) | SLC6A4HTR2AKCNH2GPR84GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |