Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 4/20 | 0.32 |
| ▸ | BCR | P11274 | 4/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984279 | 0.86 | SLC6A4 (0.35) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL19984021 | 0.85 | GAK (0.40) | SLC6A4HTR2AKCNH2MRGPRX4KDM4E | |
| SCHEMBL19984163 | 0.85 | FADS1 (0.36) | SLC6A4HTR2AKCNH2MRGPRX4SLC6A2 | |
| SCHEMBL19983885 | 0.83 | FBP1 (0.39) | SLC6A4HTR2AKCNH2ABL1BCR | |
| SCHEMBL16626075 | 0.83 | HTR6 (0.42) | SLC6A4HTR2AKCNH2EPHX2NR1H4 | |
| Hydrochloric Acid SCHEMBL16619305 | 0.82 | HTR6 (0.42) | SLC6A4HTR2AKCNH2EPHX2NR1H4 | |
| SCHEMBL19983775 | 0.82 | EGFR (0.34) | FBP1 | |
| SCHEMBL19983791 | 0.81 | KDR (0.33) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL19984029 | 0.81 | APP (0.35) | SLC6A4HTR2AKCNH2MRGPRX4 | |
| SCHEMBL16626755 | 0.78 | FBP1 (0.41) | SLC6A4HTR2AKCNH2MRGPRX4FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |