Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983954 | 0.90 | HTR2A (0.32) | KDM4E | |
| SCHEMBL19983888 | 0.89 | P2RX7 (0.31) | KDM4E | |
| SCHEMBL19983916 | 0.85 | KDM4E (0.30) | KDM4E | |
| SCHEMBL19984027 | 0.79 | MAPK14 (0.37) | — | |
| SCHEMBL19984279 | 0.78 | SLC6A4 (0.35) | — | |
| SCHEMBL19983907 | 0.78 | FPR1 (0.36) | IDO1 | |
| SCHEMBL19983937 | 0.78 | MPO (0.37) | KDM4EIDO1APP | |
| SCHEMBL16626527 | 0.77 | HTR6 (0.42) | — | |
| Hydrochloric Acid SCHEMBL16619067 | 0.77 | HTR6 (0.42) | — | |
| SCHEMBL19984127 | 0.77 | NUDT1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |