SCHEMBL19984894

SCHEMBL19984894

CCOC(=O)/C(=C/OC1C=C(C)C(=O)O1)C1CCC(C)(C)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 7/20 0.40
SIGMAR1 Q99720 2/20 0.34
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
POLB P06746 1/20 0.32
KCNH2 Q12809 1/20 0.31
GRIN2B Q13224 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21538772 0.83 SIGMAR1 (0.33) SIGMAR1ALDH1A1MAPTL3MBTL1POLB
SCHEMBL19984944 0.83 NFE2L2 (0.38) NFE2L2ALDH1A1MAPTL3MBTL1
SCHEMBL19985052 0.81 NFE2L2 (0.35) NFE2L2ALDH1A1MAPTL3MBTL1POLB
SCHEMBL21538751 0.81 NFE2L2 (0.37) NFE2L2ALDH1A1MAPT
SCHEMBL19984937 0.81 NFE2L2 (0.37) NFE2L2ALDH1A1MAPTL3MBTL1POLB
SCHEMBL21538717 0.80 NFE2L2 (0.36) NFE2L2ALDH1A1MAPT
SCHEMBL21538718 0.80 L3MBTL1 (0.38) SIGMAR1ALDH1A1MAPTL3MBTL1POLB
SCHEMBL21538770 0.79 NFE2L2 (0.37) NFE2L2L3MBTL1
SCHEMBL21538699 0.79 L3MBTL1 (0.36) NFE2L2ALDH1A1MAPTL3MBTL1POLB
SCHEMBL19984939 0.76 FFAR1 (0.38) NFE2L2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US disclosed
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-10-31 US disclosed
WO-2018050477-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 NFE2L2 2365/4885SIGMAR1 3783/4885ALDH1A1 3543/4885
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS FGF1, MST1, CDC20 NFE2L2 2365/4885SIGMAR1 3783/4885ALDH1A1 3543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.