SCHEMBL19985049

SCHEMBL19985049

CCOC(=O)/C(=C/O)C1CCOc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
POLB P06746 4/20 0.39
MGAM O43451 1/20 0.38
AMY1A P0DUB6 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
MAPT P10636 3/20 0.38
PLIN1 O60240 1/20 0.38
LMNA P02545 1/20 0.38
PLIN5 Q00G26 1/20 0.38
ABHD5 Q8WTS1 1/20 0.38
TSHR P16473 4/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
SSTR4 P31391 1/20 0.37
ALDH1A1 P00352 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21538741 0.88 GLS (0.41) MEN1KMT2APOLBMGAMAMY1A
SCHEMBL23934507 0.82 ALDH1A1 (0.43) MEN1KMT2APOLBMGAMAMY1A
SCHEMBL22325514 0.82 TSHR (0.46) MEN1KMT2APOLBMGAMAMY1A
SCHEMBL19985037 0.81 SSTR4 (0.34) MEN1KMT2APOLBMGAMAMY1A
SCHEMBL19985035 0.80 MGAM (0.34) MEN1KMT2APOLBMGAMAMY1A
SCHEMBL19985052 0.80 NFE2L2 (0.35) MEN1KMT2APOLBMGAMAMY1A
SCHEMBL19985038 0.79 PIN1 (0.46) MEN1KMT2AMAPTL3MBTL1ALDH1A1
SCHEMBL21538694 0.77 ALDH1A1 (0.43) MEN1KMT2ALMNAL3MBTL1ALDH1A1
SCHEMBL21538768 0.76 ANO1 (0.41) MEN1KMT2ALMNAL3MBTL1ALDH1A1
SCHEMBL19985034 0.76 MEN1 (0.41) MEN1KMT2APOLBGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512843-B1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-20 EP disclosed
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US disclosed
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-10-31 US disclosed
WO-2018050477-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 MEN1 3340/4885KMT2A 4196/4885POLB 3208/4885
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS FGF1, MST1, CDC20 MEN1 3340/4885KMT2A 4196/4885POLB 3208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.