SCHEMBL560256

SCHEMBL560256

CCOC(CCCN1C(=O)c2ccccc2C1=O)OCC

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MEN1 O00255 1/20 0.49
CYP1A2 P05177 1/20 0.49
CHRM2 P08172 1/20 0.49
CYP2C19 P33261 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30566000 1.00 MAPT (0.50) MAPTRAB9ASMN1; SMN2MEN1CYP1A2
SCHEMBL7338729 0.90 ALDH1A1 (0.48) MAPTRAB9ASMN1; SMN2
SCHEMBL19985874 0.86 MAOB (0.49) MAPTRAB9ASMN1; SMN2
SCHEMBL29678473 0.84 MAPT (0.53) MAPTRAB9ASMN1; SMN2MEN1CYP1A2
SCHEMBL5663071 0.84 MAPT (0.53) MAPTRAB9ASMN1; SMN2MEN1CYP1A2
SCHEMBL10204012 0.81 RAB9A (0.48) MAPTRAB9ASMN1; SMN2CYP1A2CYP2C19
SCHEMBL563821 0.80 KMT2A (0.47) RAB9AKMT2A
SCHEMBL7961062 0.80 PKM (0.39) KMT2A
SCHEMBL9800366 0.79 TDP1 (0.51) MAPTRAB9ASMN1; SMN2MEN1CYP1A2
SCHEMBL3262594 0.79 HPGD (0.49) MAPTRAB9ASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163044-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-05-22 US disclosed
EP-4452979-A1 COMPOUNDS Psylo Pty Ltd (AU) 2024-10-30 EP disclosed
WO-2023226381-A1 INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 上海英诺富成生物科技有限公司 2023-11-30 WO disclosed
US-20230348419-A1 BIAMINOQUINOLINES AND NANOFORMULATIONS FOR CANCER TREATMENT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-11-02 US disclosed
US-20230348419-A1 BIAMINOQUINOLINES AND NANOFORMULATIONS FOR CANCER TREATMENT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-11-02 US disclosed
WO-2023115165-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 WO disclosed
WO-2023115165-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 WO disclosed
WO-2021055705-A1 BIAMINOQUINOLINES AND NANOFORMULATIONS FOR CANCER TREATMENT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-03-25 WO disclosed
US-10806794-B2 Protease inhibitors having enhanced features NEKTAR THERAPEUTICS (US) 2020-10-20 US disclosed
EP-3515902-A1 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL Grünenthal GmbH (DE) 2019-07-31 EP disclosed
WO-1995024200-A1 METHOD FOR TREATING 5HT2B RECEPTOR RELATED CONDITIONS ELI LILLY AND COMPANY (US) 1995-09-14 WO disclosed
WO-1994023720-A1 TETRAHYDRO-BETA-CARBOLINES ELI LILLY AND COMPANY (US) 1994-10-27 WO disclosed
WO-1994024127-A1 INDOLE DERIVATIVES AS 5-H1-LIKE AGONISTS FOR USE IN MIGRAINE PFIZER LIMITED (GB) 1994-10-27 WO disclosed
EP-0620222-A2 Tetrahydro-beta-carbolines ELI LILLY AND COMPANY (US) 1994-10-19 EP disclosed
US-4876267-A MIGRANES GLAXO GROUP LIMITED (GB) 1989-10-24 US disclosed
US-4816470-A Heterocyclic compounds GLAXO GROUP LIMITED 1989-03-28 US disclosed
EP-0254433-A2 Indole derivatives GLAXO GROUP LIMITED (GB) 1988-01-27 EP disclosed
US-4650810-A OR INDOLE-5-THIOACETAMIDES GLAXO GROUP LIMITED (GB) 1987-03-17 US disclosed
US-4252803-A HYPOTENSIVE AGENTS, ANALGESICS GLAXO GROUP LIMITED (GB) 1981-02-24 US disclosed
US-4009328-A Aminoglycoside 66-40C, method for its manufacture, method for its use as an intermediate in the preparation of known antibiotics and novel antibacterials SCHERING CORPORATION (US) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348419-A1 BIAMINOQUINOLINES AND NANOFORMULATIONS FOR CANCER TREATMENT RECQL, NQO1, BRD4 MAPT 1301/4885RAB9A 959/4885SMN1; SMN2 3063/4885
US-10806794-B2 Protease inhibitors having enhanced features SERPINB1, SPINT2, TMPRSS15 MAPT 1280/4885RAB9A 2701/4885SMN1; SMN2 3850/4885
US-20250163044-A1 COMPOUNDS NLN, SLC18A2, PYGB MAPT 139/4885RAB9A 2210/4885SMN1; SMN2 138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.