Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MARS1 | P56192 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986718 | 0.85 | ALDH1A1 (0.42) | KDM4ESLC6A3KMT2AMEN1CDK2 | |
| SCHEMBL19986692 | 0.83 | NAMPT (0.38) | KDM4ENAMPTKMT2ASCN10AMEN1 | |
| SCHEMBL19986619 | 0.82 | NAMPT (0.37) | KDM4ENAMPTKMT2ASCN10AHDAC3 | |
| SCHEMBL19986507 | 0.78 | KMT2A (0.38) | KDM4ESLC6A3NAMPTKMT2AMEN1 | |
| SCHEMBL19986699 | 0.78 | LMNA (0.53) | NAMPTKMT2AMEN1MARS1BRD4 | |
| SCHEMBL19986705 | 0.77 | MARS1 (0.47) | SLC6A3KMT2AMEN1MARS1ALDH1A1 | |
| SCHEMBL19986671 | 0.75 | EPHX2 (0.49) | KDM4ESLC6A3KMT2AMEN1ALDH1A1 | |
| SCHEMBL19986715 | 0.75 | KMT2A (0.41) | KDM4ENAMPTKMT2AMEN1MAPT | |
| SCHEMBL19986631 | 0.75 | KMT2A (0.53) | NAMPTKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL19986446 | 0.74 | KMT2A (0.49) | KDM4ESLC6A3NAMPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |