SCHEMBL19990336

SCHEMBL19990336

Cc1c(CC2CCCO2)c(Oc2c(F)cc(C(F)(F)F)cc2Cl)nn1C(N)=O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RORC P51449 2/20 0.38
MAPK1 P28482 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
TSHR P16473 1/20 0.33
CNR2 P34972 5/20 0.33
TGFBR1 P36897 1/20 0.32
TGFBR2 P37173 1/20 0.32
GAA P10253 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 2/20 0.32
ADRB2 P07550 1/20 0.32
HTR2C P28335 1/20 0.31
SLC6A4 P31645 1/20 0.31
ALDH1A1 P00352 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1958486 0.95 RORC (0.40) RORCMAPK1SMN1; SMN2TSHRCNR2
SCHEMBL3625648 0.82 GABRB3 (0.37) SMN1; SMN2KMT2AKDM4EALDH1A1NPSR1
SCHEMBL20563894 0.77 TDP1 (0.38) SMN1; SMN2TSHRGAAKMT2AKDM4E
SCHEMBL20528672 0.76 GABRB3 (0.39) SMN1; SMN2KMT2AKDM4EALDH1A1L3MBTL1
SCHEMBL38969 0.74 MAPK1 (0.46) RORCMAPK1TSHRGAAKMT2A
SCHEMBL29768830 0.72 CNR2 (0.39) RORCMAPK1CNR2HTR2CSLC6A4
SCHEMBL2599386 0.72 CNR2 (0.39) RORCMAPK1CNR2HTR2CSLC6A4
SCHEMBL27168510 0.69 GABRP (0.35) MAPK1SMN1; SMN2GAAKMT2AKDM4E
SCHEMBL28349585 0.69 P2RY12 (0.37) RORCMAPK1SMN1; SMN2GAA
SCHEMBL39063 0.68 MAPK1 (0.48) RORCMAPK1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 US claimed
US-20210145003-A1 MIXTURES COMPRISING A HERBICIDE AND A NITRIFICATION INHIBITOR SUCH AS 2-(3,4-DIMETHYL-1H-PYRAZOL-1-YL)SUCCINIC ACID (DMPSA) OR 3,4-DIMETHYL PYRAZOLIUM GLOCOLATE (DMPG) BASF SE (DE) 2021-05-20 US claimed
US-20200359631-A1 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE OR ITS SALT AND AT LEAST ONE PROTOPORPHYRINOGEN-IX OXIDASE INHIBITOR BASF SE (DE) 2020-11-19 US claimed
EP-3664606-A1 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE OR ITS SALT AND AT LEAST ONE PROTOPORPHYRINOGEN-IX OXIDASE INHIBITOR BASF SE (DE) 2020-06-17 EP claimed
WO-2019030098-A1 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE OR ITS SALT AND AT LEAST ONE PROTOPORPHYRINOGEN-IX OXIDASE INHIBITOR BASF SE (DE) 2019-02-14 WO claimed
US-20250143309-A1 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE OR ITS SALT AND AT LEAST ONE PROTOPORPHYRINOGEN-IX OXIDASE INHIBITOR BASF SE (DE) 2025-05-08 US disclosed
US-20250143310-A1 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE OR ITS SALT AND AT LEAST ONE PROTOPORPHYRINOGEN-IX OXIDASE INHIBITOR BASF SE (DE) 2025-05-08 US disclosed
US-20250143308-A1 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE OR ITS SALT AND AT LEAST ONE PROTOPORPHYRINOGEN-IX OXIDASE INHIBITOR BASF SE (DE) 2025-05-08 US disclosed
US-12262715-B2 Herbicidal mixtures comprising L-glufosinate or its salt and at least one protoporphyrinogen-IX oxidase inhibitor BASF SE (DE) 2025-04-01 US disclosed
US-12256739-B2 Herbicidal mixtures comprising L-glufosinate or its salt and at least one protoporphyrinogen-IX oxidase inhibitor BASF SE (DE) 2025-03-25 US disclosed
US-20250072424-A1 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE OR ITS SALT AND AT LEAST ONE PROTOPORPHYRINOGEN-IX OXIDASE INHIBITOR BASF SE (DE) 2025-03-06 US disclosed
US-12041935-B2 Herbicidal mixtures comprising L-glufosinate or its salt and at least one protoporphyrinogen-IX oxidase inhibitor BASF SE (DE) 2024-07-23 US disclosed
US-20180317489-A1 Substituted Oxadiazoles for Combating Phytopathogenic Fungi BASF SE (DE) 2018-11-08 US disclosed
US-20180317491-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2018-11-08 US disclosed
US-20180317488-A1 Use of Substituted Oxadiazoles for Combating Phytopathogenic Fungi BASF SE (DE) 2018-11-08 US disclosed
US-20180317490-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2018-11-08 US disclosed
WO-2018184970-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2018-10-11 WO disclosed
EP-3338552-A1 USE OF A TETRAZOLINONE FUNGICIDE ON TRANSGENIC PLANTS BASF SE (DE) 2018-06-27 EP disclosed
EP-3339297-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2018-06-27 EP disclosed
US-20180086714-A1 Quinoline Compounds BASF SE (DE) 2018-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH RORC 792/4885MAPK1 1096/4885SMN1; SMN2 3275/4885
US-20210145003-A1 MIXTURES COMPRISING A HERBICIDE AND A NITRIFICATION INHIBITOR SUCH AS 2-(3,4-DIMETHYL-1H-PYRAZOL-1-YL)SUCCINIC ACID (DMPSA) OR 3,4-DIMETHYL PYRAZOLIUM GLOCOLATE (DMPG) GLO1, DDT, GMDS RORC 4535/4885MAPK1 3768/4885SMN1; SMN2 1052/4885
US-20180317488-A1 Use of Substituted Oxadiazoles for Combating Phytopathogenic Fungi CYP51A1, OSR1, FOXO3 RORC 1340/4885MAPK1 492/4885SMN1; SMN2 3085/4885
US-20180317490-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI PAOX, NOXO1, CYP51A1 RORC 1214/4885MAPK1 1012/4885SMN1; SMN2 3386/4885
US-20180317491-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI CYP51A1, OSR1, PAOX RORC 1099/4885MAPK1 363/4885SMN1; SMN2 3029/4885
US-20180317489-A1 Substituted Oxadiazoles for Combating Phytopathogenic Fungi CYP51A1, OSR1, NOX1 RORC 1474/4885MAPK1 397/4885SMN1; SMN2 2870/4885
US-20180086714-A1 Quinoline Compounds NQO2, NQO1, SQOR RORC 2071/4885MAPK1 2503/4885SMN1; SMN2 3325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.