Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1608836 | 0.83 | ALDH1A1 (0.46) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL28786000 | 0.73 | MGLL (0.38) | L3MBTL1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL10973243 | 0.73 | KMT2A (0.47) | L3MBTL1CYP1A2CYP2C19KMT2AKDM4E | |
| SCHEMBL721638 | 0.73 | KMT2A (0.37) | L3MBTL1KMT2ASLC1A2MAPT | |
| SCHEMBL29032349 | 0.72 | L3MBTL1 (0.50) | LMNAL3MBTL1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3046367 | 0.72 | CTSD (0.40) | LMNAL3MBTL1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28286235 | 0.70 | LMNA (0.41) | LMNAKMT2AMAPTSLC6A4SLC6A2 | |
| SCHEMBL9702157 | 0.69 | CTSD (0.50) | LMNAL3MBTL1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9562580 | 0.68 | MGLL (0.46) | LMNAKMT2AMAPT | |
| SCHEMBL8871482 | 0.68 | ALDH1A1 (0.41) | LMNAL3MBTL1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515476-A1 | FUSION COMPRISING A CELL PENETRATING PEPTIDE, A MULTI EPITOPE AND A TLR PEPTIDE AGONIST FOR TREATMENT OF CANCER | Amal Therapeutics SA (CH) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018055060-A1 | FUSION COMPRISING A CELL PENETRATING PEPTIDE, A MULTI EPITOPE AND A TLR PEPTIDE AGONIST FOR TREATMENT OF CANCER | AMAL THERAPEUTICS SA (CH) | 2018-03-29 | — | — | WO | disclosed |