Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 5/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002981 | 0.80 | KDM4E (0.55) | NAMPTLMNA | |
| SCHEMBL20003097 | 0.78 | HSD11B1 (0.59) | MGLL | |
| SCHEMBL6981541 | 0.73 | NPC1 (0.67) | DPP4DPP8LMNAPDE2ACCR3 | |
| SCHEMBL16087283 | 0.73 | L3MBTL1 (0.63) | LMNARORC | |
| SCHEMBL31428431 | 0.71 | CAPN1 (0.55) | NAMPTDPP4DPP8LMNAPDE2A | |
| SCHEMBL16002936 | 0.71 | PLK1 (0.55) | DPP4DPP8LMNAPDE2ACCR3 | |
| SCHEMBL6986208 | 0.70 | HPGD (0.71) | DPP4DPP8LMNAPDE2A | |
| SCHEMBL6251264 | 0.70 | PRKAA2 (0.56) | LMNACCR3 | |
| SCHEMBL13889099 | 0.70 | L3MBTL3 (0.67) | DPP4DPP8CCR3 | |
| SCHEMBL28256059 | 0.69 | HPGD (0.57) | DPP4DPP8LMNAPDE2ACCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |