Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002854 | 0.83 | RORC (0.42) | TSHRPKM | |
| SCHEMBL20002664 | 0.82 | TSHR (0.41) | TSHRPKMNPC1RAB9AATM | |
| SCHEMBL20002631 | 0.74 | HSD11B1 (0.33) | NOTUMPKMNPC1RAB9AATM | |
| SCHEMBL20002873 | 0.72 | ACHE (0.56) | BCHEACHEBACE1 | |
| SCHEMBL20002582 | 0.72 | ACHE (0.56) | BCHEACHEBACE1 | |
| SCHEMBL20002698 | 0.70 | HSD11B1 (0.47) | TSHR | |
| SCHEMBL20002706 | 0.70 | HSD11B1 (0.47) | TSHR | |
| SCHEMBL29051099 | 0.70 | RAB9A (0.49) | PDE4BTACR1NPC1RAB9AATM | |
| SCHEMBL29051117 | 0.70 | RAB9A (0.49) | PDE4BTACR1NPC1RAB9AATM | |
| SCHEMBL29051096 | 0.70 | RAB9A (0.49) | PDE4BTACR1NPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |