Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 9/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002870 | 0.86 | PDK2 (0.38) | PDK2DRD2DRD4DRD3RORC | |
| SCHEMBL20002917 | 0.80 | MEN1 (0.47) | ALDH1A1POLB | |
| SCHEMBL20002210 | 0.78 | RORC (0.44) | PDK2DRD2DRD4DRD3RORC | |
| SCHEMBL20002956 | 0.78 | RORC (0.44) | PDK2DRD2DRD4DRD3RORC | |
| SCHEMBL20002167 | 0.76 | KDM1A (0.40) | RORCALDH1A1SMN1; SMN2 | |
| SCHEMBL20002280 | 0.76 | TACR1 (0.40) | RORC | |
| SCHEMBL20002990 | 0.76 | RORC (0.40) | RORC | |
| SCHEMBL20002564 | 0.75 | NAMPT (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL20002286 | 0.75 | TACR1 (0.45) | RORC | |
| SCHEMBL20002495 | 0.75 | RORC (0.40) | RORCALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |