Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 8/20 | 0.41 |
| ▸ | MMP9 | P14780 | 8/20 | 0.41 |
| ▸ | MMP8 | P22894 | 5/20 | 0.41 |
| ▸ | MMP12 | P39900 | 5/20 | 0.41 |
| ▸ | MMP14 | P50281 | 5/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP7 | P09237 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008646 | 0.89 | ITGB3 (0.43) | ITGB3ITGA2BMMP2MMP9MMP8 | |
| SCHEMBL20008648 | 0.88 | MMP9 (0.43) | ITGB3ITGA2BMMP2MMP9MMP8 | |
| SCHEMBL20008696 | 0.80 | ITGB3 (0.52) | ITGB3ITGA2BNOD1 | |
| SCHEMBL20012060 | 0.78 | ITGB3 (0.38) | ITGB3ITGA2BMMP2MMP9MMP8 | |
| SCHEMBL20008649 | 0.77 | MMP9 (0.46) | ITGB3ITGA2BMMP2MMP9MMP8 | |
| SCHEMBL7415627 | 0.71 | ITGB3 (0.49) | ITGB3ITGA2BMMP2ALDH1A1LMNA | |
| SCHEMBL7415632 | 0.71 | ITGB3 (0.49) | ITGB3ITGA2BMMP2ALDH1A1LMNA | |
| SCHEMBL18720249 | 0.71 | CASP3 (0.40) | ITGB3ITGA2BMMP2MMP9MMP8 | |
| SCHEMBL13165330 | 0.69 | NOD1 (0.44) | NOD1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL12664935 | 0.69 | NOD1 (0.44) | NOD1NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | ITGB3 2592/4885ITGA2B 2485/4885MMP2 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.