Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 19/20 | 0.34 |
| ▸ | BRAF | P15056 | 17/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008457 | 0.87 | L3MBTL1 (0.34) | RAF1BRAFCRHR1 | |
| SCHEMBL20008319 | 0.82 | — | — | |
| SCHEMBL20010275 | 0.75 | — | — | |
| SCHEMBL20008335 | 0.70 | RAF1 (0.49) | RAF1BRAF | |
| SCHEMBL20008434 | 0.66 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL20009455 | 0.61 | TLR8 (0.32) | — | |
| SCHEMBL22788370 | 0.59 | CNR2 (0.39) | CRHR1 | |
| SCHEMBL22153071 | 0.59 | GRIN2B (0.35) | — | |
| SCHEMBL20008460 | 0.58 | RAF1 (0.41) | RAF1BRAF | |
| SCHEMBL20008538 | 0.58 | DRD2 (0.49) | RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |