Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22788370 | 0.63 | CNR2 (0.39) | — | |
| SCHEMBL20008457 | 0.63 | L3MBTL1 (0.34) | — | |
| SCHEMBL24799544 | 0.58 | PYCR1 (0.44) | — | |
| SCHEMBL10111222 | 0.57 | CRHR1 (0.41) | — | |
| SCHEMBL20428088 | 0.55 | HTR1A (0.45) | — | |
| SCHEMBL1688843 | 0.54 | CRHR1 (0.43) | — | |
| SCHEMBL24649608 | 0.53 | HRH3 (0.55) | — | |
| SCHEMBL197716 | 0.53 | ALDH1A1 (0.52) | — | |
| SCHEMBL18576167 | 0.53 | TSHR (0.37) | — | |
| Lithium Ion SCHEMBL19732759 | 0.53 | CRHR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |