Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468461 | 0.83 | LMNA (0.46) | SLC22A12RPS6KA3MAPK14LMNAMAPT | |
| SCHEMBL15468467 | 0.80 | SLC22A12 (0.44) | SLC22A12RPS6KA3RAB9ANPC1GCGR | |
| SCHEMBL20020060 | 0.80 | RPS6KA3 (0.68) | SLC22A12RPS6KA3CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL18162722 | 0.76 | CYP11B1 (0.50) | SLC22A12RPS6KA3RAB9ANPC1CYP11B1 | |
| SCHEMBL16938695 | 0.76 | MAPT (0.55) | SLC22A12RPS6KA3RAB9ANPC1CACNA1B | |
| SCHEMBL15468459 | 0.76 | RPS6KA3 (0.39) | SLC22A12RPS6KA3GAAKDM4ESMN1; SMN2 | |
| SCHEMBL4948169 | 0.72 | DGAT1 (0.42) | SLC22A12RPS6KA3GAARAB9ANPC1 | |
| SCHEMBL18162728 | 0.72 | GRM4 (0.45) | SLC22A12RPS6KA3GAARAB9ACACNA1B | |
| SCHEMBL8588230 | 0.70 | ALDH1A1 (0.50) | GAARAB9ANPC1KDM4ELMNA | |
| SCHEMBL15468462 | 0.70 | SLC22A12 (0.57) | SLC22A12GAARAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975025-B1 | THIOACETATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES INC (US) | 2018-04-04 | — | — | EP | disclosed |