Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.62 |
| ▸ | MMP12 | P39900 | 3/20 | 0.58 |
| ▸ | MMP1 | P03956 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.55 |
| ▸ | MMP2 | P08253 | 5/20 | 0.54 |
| ▸ | MMP9 | P14780 | 4/20 | 0.54 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | MMP14 | P50281 | 2/20 | 0.54 |
| ▸ | MMP3 | P08254 | 3/20 | 0.54 |
| ▸ | MMP13 | P45452 | 3/20 | 0.54 |
| ▸ | MMP7 | P09237 | 2/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.54 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674105 | 0.89 | ALDH1A1 (0.66) | ALDH1A1GRIA4HSP90AA1HSP90AB1PDK1 | |
| Hydrochloric Acid SCHEMBL14638221 | 0.87 | ALDH1A1 (0.64) | ALDH1A1GAAGRIA4HSP90AA1HSP90AB1 | |
| SCHEMBL6326386 | 0.87 | MMP1 (0.59) | ALDH1A1GPR55MMP12MMP1GAA | |
| SCHEMBL15087835 | 0.87 | MMP1 (0.59) | ALDH1A1GPR55MMP12MMP1GAA | |
| SCHEMBL7260455 | 0.86 | GBA1 (0.68) | ALDH1A1GPR55MMP1GAAMMP2 | |
| SCHEMBL890706 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MMP1GAAMMP2MMP9 | |
| SCHEMBL28129548 | 0.85 | CA1 (0.71) | ALDH1A1MMP1GAAMMP2MMP9 | |
| SCHEMBL890942 | 0.84 | GPR55 (0.60) | ALDH1A1GPR55MMP12MMP1GAA | |
| SCHEMBL28719400 | 0.83 | MMP2 (0.56) | ALDH1A1MMP12MMP1GAAADAMTS4 | |
| SCHEMBL5870281 | 0.80 | MMP2 (0.58) | GPR55MMP12MMP1GAAADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527152-A | Biphenylsulfonamide compound and method for preventing and treating crop pests by using same | 西北农林科技大学 | 2021-10-22 | — | — | CN | claimed |
| CN-113527152-A | Biphenylsulfonamide compound and method for preventing and treating crop pests by using same | 西北农林科技大学 | 2021-10-22 | — | — | CN | disclosed |
| US-20180093960-A1 | METHOD OF INHIBITING APOLIPOPROTEIN-E EXPRESSION WHILE INCREASING EXPRESSION OF AT LEAST ONE OF LDL-RECEPTOR PROTEIN OR ABCA1 PROTEIN COMPRISING ADMINISTERING A SMALL COMPOUND | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2018-04-05 | — | — | US | disclosed |
| US-20180093960-A1 | METHOD OF INHIBITING APOLIPOPROTEIN-E EXPRESSION WHILE INCREASING EXPRESSION OF AT LEAST ONE OF LDL-RECEPTOR PROTEIN OR ABCA1 PROTEIN COMPRISING ADMINISTERING A SMALL COMPOUND | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093960-A1 | METHOD OF INHIBITING APOLIPOPROTEIN-E EXPRESSION WHILE INCREASING EXPRESSION OF AT LEAST ONE OF LDL-RECEPTOR PROTEIN OR ABCA1 PROTEIN COMPRISING ADMINISTERING A SMALL COMPOUND | LDLR, APOB, NR1H2 | ALDH1A1 3152/4885GPR55 1266/4885MMP12 1518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.