Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | NMT2 | O60551 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20022932 | 0.78 | LMNA (0.44) | CNR1LMNAPKMFAAHMEN1 | |
| SCHEMBL20048862 | 0.74 | ALDH1A1 (0.47) | CNR1LMNAPKMFAAHMAPK1 | |
| SCHEMBL26786256 | 0.73 | LMNA (0.34) | CNR1LMNAPKMFAAHMEN1 | |
| SCHEMBL18029409 | 0.72 | TSHR (0.35) | LMNAFAAHMEN1MAPK1KMT2A | |
| SCHEMBL18029408 | 0.72 | MEN1 (0.33) | FAAHMEN1MAPK1KMT2AHPGD | |
| SCHEMBL8942527 | 0.71 | CNR1 (0.54) | CNR1LMNAPKMFAAHMEN1 | |
| SCHEMBL13328249 | 0.71 | LMNA (0.60) | CNR1LMNAPKMFAAHHPGD | |
| SCHEMBL16979551 | 0.70 | ALDH1A1 (0.33) | FAAHMEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL21029696 | 0.69 | FAAH (0.58) | CNR1LMNAPKMFAAHMEN1 | |
| SCHEMBL14355671 | 0.69 | FAAH (0.61) | FAAHMEN1MAPK1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827744-B2 | Bottlebrush copolymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-11-28 | — | — | US | disclosed |
| US-20180094099-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180094099-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | TRIB1, TRIB2, ABCB11 | CNR1 636/4885LMNA 4117/4885PKM 3677/4885 |
| US-11827744-B2 | Bottlebrush copolymers and uses thereof | TRIB1, TRIB2, ABCB11 | CNR1 636/4885LMNA 4117/4885PKM 3677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.