Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 5/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 5/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.31 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409842 | 0.92 | SIGMAR1 (0.33) | SIGMAR1GNAI3GNAI1PRSS1TPSAB1 | |
| SCHEMBL22001231 | 0.85 | GNAI3 (0.33) | SIGMAR1GNAI3GNAI1PRSS1TPSAB1 | |
| SCHEMBL22388961 | 0.82 | NR2F2 (0.33) | SIGMAR1GNAI3GNAI1PRSS1TPSAB1 | |
| SCHEMBL15443875 | 0.77 | GNAI3 (0.39) | GNAI3GNAI1PRSS1TPSAB1TPSD1 | |
| SCHEMBL20019652 | 0.76 | GNAI3 (0.37) | GNAI3GNAI1PRSS1TPSAB1TPSD1 | |
| SCHEMBL22620788 | 0.76 | GNAI3 (0.40) | GNAI3GNAI1PRSS1TPSAB1TPSD1 | |
| SCHEMBL20032529 | 0.75 | GNAI3 (0.40) | GNAI3GNAI1PRSS1TPSAB1TPSD1 | |
| SCHEMBL15355591 | 0.74 | GNAI3 (0.41) | SIGMAR1GNAI3GNAI1PRSS1TPSAB1 | |
| SCHEMBL14980274 | 0.73 | GNAI3 (0.44) | GNAI3GNAI1PRSS1TPSAB1TPSD1 | |
| SCHEMBL27336659 | 0.70 | GNAI3 (0.41) | GNAI3GNAI1PRSS1TPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180092938-A1 | OLIGONUCLEOTIDE ANALOGUES TARGETING HUMAN LMNA | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180092938-A1 | OLIGONUCLEOTIDE ANALOGUES TARGETING HUMAN LMNA | LMNB2, LMNA, LMNB1 | SIGMAR1 3742/4885GNAI3 1384/4885GNAI1 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.