Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042752 | 0.88 | HPGD (0.47) | HPGDP2RX7MAPTMEN1ALDH1A1 | |
| SCHEMBL20042886 | 0.81 | HPGD (0.49) | HPGDP2RX7KMT2ATACR3HTR1A | |
| SCHEMBL20042667 | 0.81 | TACR3 (0.46) | P2RX7TACR3HTR1A | |
| SCHEMBL20042887 | 0.81 | GPR6 (0.42) | HPGDP2RX7MAPTALDH1A1 | |
| SCHEMBL20042671 | 0.79 | P2RX7 (0.45) | HPGDP2RX7MAPTALDH1A1KMT2A | |
| SCHEMBL20042792 | 0.79 | TACR3 (0.46) | HPGDP2RX7MAPTMEN1KMT2A | |
| SCHEMBL20042880 | 0.78 | P2RX7 (0.40) | HPGDP2RX7MAPTMEN1ALDH1A1 | |
| SCHEMBL20042823 | 0.78 | P2RX7 (0.45) | HPGDP2RX7MEN1ALDH1A1LMNA | |
| SCHEMBL20042862 | 0.78 | HPGD (0.48) | HPGDP2RX7MAPTMEN1ALDH1A1 | |
| SCHEMBL20042680 | 0.77 | GPR6 (0.44) | HPGDP2RX7MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |