Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042749 | 0.84 | PKM (0.43) | HPGDHTR1AMAPTMEN1ALDH1A1 | |
| SCHEMBL20042752 | 0.83 | HPGD (0.47) | HPGDMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL20042920 | 0.79 | GRM5 (0.41) | HTR1AP2RX7 | |
| SCHEMBL20042741 | 0.78 | HPGD (0.44) | HPGDHTR1AMAPTMEN1ALDH1A1 | |
| SCHEMBL20042886 | 0.77 | HPGD (0.49) | HPGDHTR1AKMT2AP2RX7TSHR | |
| SCHEMBL20042887 | 0.76 | GPR6 (0.42) | HPGDMAPTALDH1A1P2RX7TSHR | |
| SCHEMBL20042667 | 0.74 | TACR3 (0.46) | HTR1AP2RX7TACR3 | |
| SCHEMBL20042671 | 0.74 | P2RX7 (0.45) | HPGDMAPTALDH1A1KMT2AP2RX7 | |
| SCHEMBL20042680 | 0.73 | GPR6 (0.44) | HPGDMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL20042803 | 0.73 | GPR6 (0.40) | HPGDMAPTALDH1A1TSHRSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |