Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 13/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042742 | 0.83 | PROKR1 (0.35) | P2RX7KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL20042857 | 0.82 | PROKR1 (0.35) | KDM4ESMN1; SMN2PIK3CD | |
| SCHEMBL20042851 | 0.81 | P2RX7 (0.46) | P2RX7SMN1; SMN2KMT2A | |
| SCHEMBL20042982 | 0.81 | P2RX7 (0.46) | P2RX7SMN1; SMN2KMT2A | |
| SCHEMBL20042958 | 0.81 | TACR3 (0.42) | — | |
| SCHEMBL20042865 | 0.81 | TACR3 (0.42) | — | |
| SCHEMBL20042766 | 0.81 | TACR3 (0.36) | P2RX7KDM4ESMN1; SMN2 | |
| SCHEMBL20042867 | 0.79 | PROKR1 (0.39) | KDM4ESMN1; SMN2KMT2AMAPTPIK3CD | |
| SCHEMBL20042896 | 0.79 | GRM5 (0.38) | P2RX7 | |
| SCHEMBL20042868 | 0.78 | P2RX7 (0.35) | P2RX7KDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |