Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042791 | 0.75 | SMN1; SMN2 (0.37) | NPY5RKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL20042797 | 0.75 | LMNA (0.42) | MTORKDM4ESMN1; SMN2CHRM4 | |
| SCHEMBL20042804 | 0.74 | ALDH1A1 (0.40) | NPY5RKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL20042870 | 0.72 | KDM4E (0.35) | NPY5RMTORKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL20042800 | 0.70 | CNR1 (0.45) | MTORSMN1; SMN2CHRM4MEN1KMT2A | |
| SCHEMBL20042806 | 0.70 | CNR1 (0.47) | SMN1; SMN2CHRM4MEN1KMT2A | |
| SCHEMBL20042690 | 0.70 | GFER (0.41) | CHRM4MEN1KMT2A | |
| SCHEMBL20042873 | 0.70 | P2RX7 (0.38) | KDM4EMEN1KMT2A | |
| SCHEMBL20042764 | 0.69 | CNR1 (0.49) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20042670 | 0.69 | MTOR (0.47) | MTORSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |