Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042748 | 0.90 | NPC1 (0.49) | GFERALDH1A1MEN1KMT2AGPBAR1 | |
| SCHEMBL20042830 | 0.88 | ME2 (0.43) | ALDH1A1MEN1KMT2AGPBAR1NPC1 | |
| SCHEMBL20042688 | 0.88 | C3AR1 (0.45) | CHRM4MEN1KMT2A | |
| SCHEMBL20042747 | 0.84 | GRIN1 (0.39) | KMT2AGPBAR1 | |
| SCHEMBL20042703 | 0.83 | PTGDR2 (0.37) | CHRM4 | |
| SCHEMBL20042673 | 0.81 | MAPK1 (0.38) | — | |
| SCHEMBL20042714 | 0.78 | CHRM4 (0.43) | CHRM4ALDH1A1KMT2ALMNA | |
| SCHEMBL20042654 | 0.77 | HSD11B1 (0.41) | CHRM4ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL20042834 | 0.75 | CHRM4 (0.56) | CHRM4ALDH1A1LMNA | |
| SCHEMBL20042651 | 0.74 | CHRM4 (0.52) | CHRM4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |