Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25893559 | 0.96 | LMNA (0.38) | LMNATSHRMAP2K2MAP2K1TP53 | |
| SCHEMBL21662058 | 0.91 | TP53 (0.45) | TP53SMN1; SMN2KMT2AHTT | |
| SCHEMBL20044096 | 0.89 | TP53 (0.36) | TP53SMN1; SMN2PARP1KMT2AHTT | |
| SCHEMBL20044635 | 0.85 | ROCK1 (0.39) | LMNATSHRMAP2K2MAP2K1EPHX2 | |
| SCHEMBL20044075 | 0.85 | RAB9A (0.42) | LMNASMN1; SMN2EPHX2GAAKMT2A | |
| SCHEMBL20043950 | 0.85 | MEN1 (0.43) | LMNATSHRTP53SMN1; SMN2EPHX2 | |
| SCHEMBL20043885 | 0.85 | LMNA (0.35) | LMNATSHRGLAGAA | |
| SCHEMBL20044108 | 0.85 | KDM4E (0.38) | TP53SMN1; SMN2GAAPARP1KMT2A | |
| SCHEMBL20043917 | 0.84 | ALDH1A1 (0.41) | LMNATSHREPHX2GAA | |
| SCHEMBL24310398 | 0.84 | THRB (0.42) | LMNASMN1; SMN2EPHX2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220127229-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2022-04-28 | — | — | US | disclosed |
| US-11180453-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200347017-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2020-11-05 | — | — | US | disclosed |
| US-10654804-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2020-05-19 | — | — | US | disclosed |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2018-04-12 | — | — | US | disclosed |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | LMNA 3917/4885TSHR 1106/4885MAP2K2 3281/4885 |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | LMNA 3917/4885TSHR 1106/4885MAP2K2 3281/4885 |
| US-10654804-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | LMNA 3917/4885TSHR 1106/4885MAP2K2 3281/4885 |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | LMNA 3944/4885TSHR 1114/4885MAP2K2 3256/4885 |
| US-20220127229-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | LMNA 3917/4885TSHR 1106/4885MAP2K2 3281/4885 |
| US-20200347017-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | LMNA 3917/4885TSHR 1106/4885MAP2K2 3281/4885 |
| US-11180453-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | LMNA 3917/4885TSHR 1106/4885MAP2K2 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.