Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20044343 | 0.95 | TP53 (0.39) | TP53P2RX7CHRM3MEN1KMT2A | |
| SCHEMBL22986865 | 0.93 | TP53 (0.40) | TP53P2RX7CHRM3MEN1KMT2A | |
| SCHEMBL22621472 | 0.93 | TP53 (0.40) | TP53P2RX7CHRM3MEN1KMT2A | |
| SCHEMBL20044082 | 0.92 | MEN1 (0.43) | TP53P2RX7MDM2CHRM3MEN1 | |
| SCHEMBL20044085 | 0.91 | THRB (0.39) | TP53P2RX7MDM2CHRM3MEN1 | |
| SCHEMBL20043948 | 0.89 | TP53 (0.38) | TP53P2RX7CHRM3MEN1KMT2A | |
| SCHEMBL25893566 | 0.89 | TP53 (0.38) | TP53P2RX7CHRM3MEN1KMT2A | |
| SCHEMBL20044740 | 0.89 | TP53 (0.39) | TP53P2RX7CHRM3MEN1KMT2A | |
| SCHEMBL20044727 | 0.89 | RAB9A (0.37) | TP53MDM2MEN1KMT2AALDH1A1 | |
| SCHEMBL20043988 | 0.88 | TP53 (0.41) | TP53CHRM3MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220127229-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2022-04-28 | — | — | US | disclosed |
| US-11180453-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200347017-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2020-11-05 | — | — | US | disclosed |
| US-10654804-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2020-05-19 | — | — | US | disclosed |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2018-04-12 | — | — | US | disclosed |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | TP53 1193/4885P2RX7 866/4885MDM2 301/4885 |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | TP53 1193/4885P2RX7 866/4885MDM2 301/4885 |
| US-10654804-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | TP53 1193/4885P2RX7 866/4885MDM2 301/4885 |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | TP53 1230/4885P2RX7 869/4885MDM2 311/4885 |
| US-20220127229-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | TP53 1193/4885P2RX7 866/4885MDM2 301/4885 |
| US-20200347017-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | TP53 1193/4885P2RX7 866/4885MDM2 301/4885 |
| US-11180453-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | TP53 1193/4885P2RX7 866/4885MDM2 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.