Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4658597 | 1.00 | FDPS (0.45) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL14874694 | 1.00 | FDPS (0.45) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL4636202 | 1.00 | FDPS (0.45) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL4661052 | 1.00 | FDPS (0.45) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL20746314 | 1.00 | FDPS (0.45) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL20746483 | 1.00 | FDPS (0.45) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL20746312 | 1.00 | FDPS (0.45) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL20746506 | 1.00 | FDPS (0.45) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL20746396 | 1.00 | FDPS (0.45) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL28728575 | 1.00 | FDPS (0.45) | FDPSSMPD1CES2GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107441766-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2021-06-08 | — | — | CN | claimed |
| CN-107619950-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2021-04-20 | — | — | CN | claimed |
| CN-107447117-B | Extraction composition, extraction system, extraction method and back extraction method | 中国科学院上海有机化学研究所 | 2021-01-19 | — | — | CN | claimed |
| CN-107447109-B | Extraction composition, extraction system, extraction method and back extraction method | 中国科学院上海有机化学研究所 | 2020-08-07 | — | — | CN | claimed |
| CN-107619934-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2020-08-07 | — | — | CN | claimed |
| CN-107619933-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2020-08-07 | — | — | CN | claimed |
| CN-107619930-B | Application of amide compounds, extraction composition containing amide compounds and extraction system | 中国科学院上海有机化学研究所 | 2020-08-07 | — | — | CN | claimed |
| US-11702401-B2 | Compounds and methods of use | MEDIVATION TECHNOLOGIES LLC (US) | 2023-07-18 | — | — | US | disclosed |
| US-20230140395-A1 | NOVEL IMIDAZOLE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND USE THEREOF | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) | 2023-05-04 | — | — | US | disclosed |
| US-20230067355-A1 | 1,2,3,8,9,9a-hexahydro-5H-pyrrolo[1,2-a]azepin-5-one Derivatives Useful As Factor XIa Inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-02 | — | — | US | disclosed |
| US-20220000847-A1 | Compounds and Methods of Use | MEDIVATION TECHNOLOGIES LLC (US) | 2022-01-06 | — | — | US | disclosed |
| US-11066413-B2 | Aminopyrimidine five-membered heterocyclic compound, and intermediate, preparation method, pharmaceutical composition and application thereof | GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. (CN) | 2021-07-20 | — | — | US | disclosed |
| CN-107441766-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2021-06-08 | — | — | CN | disclosed |
| CN-107619934-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2020-08-07 | — | — | CN | disclosed |
| CN-107447109-B | Extraction composition, extraction system, extraction method and back extraction method | 中国科学院上海有机化学研究所 | 2020-08-07 | — | — | CN | disclosed |
| CN-107619934-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2020-08-07 | — | — | CN | disclosed |
| US-20200048270-A1 | AMINOPYRIMIDINE FIVE-MEMBERED HETEROCYCLIC COMPOUND, AND INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. (CN) | 2020-02-13 | — | — | US | disclosed |
| US-20190262342-A1 | COMBINATION THERAPIES FOR TREATMENT OF CANCER | ARAXES PHARMA LLC | 2019-08-29 | — | — | US | disclosed |
| US-20190016896-A1 | NOVEL RHODAMINE DYES AND CONJUGATES | PHARMACOPHOTONICS, INC. D/B/A FAST DIAGNOSTICS | 2019-01-17 | — | — | US | disclosed |
| US-20180098983-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230067355-A1 | 1,2,3,8,9,9a-hexahydro-5H-pyrrolo[1,2-a]azepin-5-one Derivatives Useful As Factor XIa Inhibitors | SERPINE1, SERPINC1, F11 | FDPS 1415/4885SMPD1 992/4885CES2 3644/4885 |
| US-20200048270-A1 | AMINOPYRIMIDINE FIVE-MEMBERED HETEROCYCLIC COMPOUND, AND INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | ADORA2A, ADORA2B, ADORA3 | FDPS 1170/4885SMPD1 2966/4885CES2 3817/4885 |
| US-20220000847-A1 | Compounds and Methods of Use | TGFB2, TGFB1, HDGF | FDPS 1451/4885SMPD1 169/4885CES2 2501/4885 |
| US-20180098983-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | PIK3CA, AKT3, PIK3C2A | FDPS 1614/4885SMPD1 452/4885CES2 893/4885 |
| US-20190016896-A1 | NOVEL RHODAMINE DYES AND CONJUGATES | RDX, CIT, RCN1 | FDPS 2677/4885SMPD1 4053/4885CES2 1193/4885 |
| US-11702401-B2 | Compounds and methods of use | TGFB2, TGFB1, HDGF | FDPS 1451/4885SMPD1 169/4885CES2 2501/4885 |
| US-20190262342-A1 | COMBINATION THERAPIES FOR TREATMENT OF CANCER | KRAS, TP53, HRAS | FDPS 3606/4885SMPD1 1949/4885CES2 4739/4885 |
| US-20230140395-A1 | NOVEL IMIDAZOLE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND USE THEREOF | MAPKAPK3, MAPK3, MAP3K3 | FDPS 3239/4885SMPD1 2842/4885CES2 4734/4885 |
| US-11066413-B2 | Aminopyrimidine five-membered heterocyclic compound, and intermediate, preparation method, pharmaceutical composition and application thereof | ADORA2A, ADORA2B, ADORA3 | FDPS 1170/4885SMPD1 2966/4885CES2 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.