SCHEMBL20061899

SCHEMBL20061899

C=C(C)C(=O)OCCOC(=O)c1cc(Oc2ccc(C(=O)O)c(C(=O)OCCOC(=O)C(=C)C)c2)ccc1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 4/20 0.48
▸ TDP1 Q9NUW8 4/20 0.48
▸ APEX1 P27695 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.41
▸ THRB P10828 1/20 0.40
▸ SERPINE1 P05121 1/20 0.38
▸ HPSE Q9Y251 1/20 0.38
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ KDM4E B2RXH2 2/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ MAPT P10636 1/20 0.36
▸ TSHR P16473 4/20 0.36
▸ LMNA P02545 1/20 0.35
▸ PYGM P11217 2/20 0.35
▸ PYGL P06737 1/20 0.35
▸ ELANE P08246 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20061898 0.97 TDP1 (0.46) POLBTDP1APEX1HTTALDH1A1
SCHEMBL19795529 0.95 TDP1 (0.48) POLBTDP1APEX1HTTALDH1A1
SCHEMBL14502945 0.90 TDP1 (0.44) POLBTDP1APEX1HTTALDH1A1
SCHEMBL24245300 0.89 POLB (0.45) POLBTDP1APEX1HTTALDH1A1
SCHEMBL17272662 0.86 TDP1 (0.48) POLBTDP1APEX1HTTALDH1A1
SCHEMBL23520516 0.86 TDP1 (0.41) POLBTDP1APEX1HTTALDH1A1
SCHEMBL543628 0.85 POLB (0.56) POLBTDP1APEX1HTTALDH1A1
SCHEMBL14262501 0.85 POLB (0.49) POLBTDP1APEX1HTTALDH1A1
SCHEMBL9906831 0.85 POLB (0.46) POLBTDP1APEX1HTTTHRB
SCHEMBL20115310 0.85 POLB (0.39) POLBTDP1APEX1HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190332012-A9 PHOTOSENSITIVE RESIN COMPOSITION, POLYAMIDE RESIN, METHOD FOR PRODUCING POLYAMIDE RESIN, COMPOUND, METHOD FOR PRODUCING COMPOUND, METHOD FOR PRODUCING CURED FILM, AND CURED FILM UBE CORPORATION (JP) 2019-10-31 — — US disclosed
US-20180107114-A1 PHOTOSENSITIVE RESIN COMPOSITION, POLYAMIDE RESIN, METHOD FOR PRODUCING POLYAMIDE RESIN, COMPOUND, METHOD FOR PRODUCING COMPOUND, METHOD FOR PRODUCING CURED FILM, AND CURED FILM TOKYO OHKA KOGYO CO LTD (JP) 2018-04-19 — — US disclosed
US-20180107114-A1 PHOTOSENSITIVE RESIN COMPOSITION, POLYAMIDE RESIN, METHOD FOR PRODUCING POLYAMIDE RESIN, COMPOUND, METHOD FOR PRODUCING COMPOUND, METHOD FOR PRODUCING CURED FILM, AND CURED FILM TOKYO OHKA KOGYO CO LTD (JP) 2018-04-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180107114-A1 PHOTOSENSITIVE RESIN COMPOSITION, POLYAMIDE RESIN, METHOD FOR PRODUCING POLYAMIDE RESIN, COMPOUND, METHOD FOR PRODUCING COMPOUND, METHOD FOR PRODUCING CURED FILM, AND CURED FILM RARA, LCP1, CUTA POLB 3523/4885TDP1 3314/4885APEX1 2902/4885
US-20190332012-A9 PHOTOSENSITIVE RESIN COMPOSITION, POLYAMIDE RESIN, METHOD FOR PRODUCING POLYAMIDE RESIN, COMPOUND, METHOD FOR PRODUCING COMPOUND, METHOD FOR PRODUCING CURED FILM, AND CURED FILM RARA, LCP1, CUTA POLB 3523/4885TDP1 3314/4885APEX1 2902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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