SCHEMBL20072345

SCHEMBL20072345

CC(=O)N(C(C)C)C1CCOCC1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 3/20 0.56
ALDH1A1 P00352 1/20 0.31
TRPM8 Q7Z2W7 1/20 0.30
BCL2A1 Q16548 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17190669 0.85 PIK3CD (0.37) PIK3CDALDH1A1TRPM8
SCHEMBL7980290 0.82 PIK3CD (0.46) PIK3CD
SCHEMBL9462834 0.81 ADH1B (0.42) PIK3CDALDH1A1TRPM8
SCHEMBL5987490 0.79 PIK3CD (0.47) PIK3CDALDH1A1
SCHEMBL11532323 0.79 ADH1C (0.45) ALDH1A1TRPM8
SCHEMBL15342467 0.78 L3MBTL3 (0.34) PIK3CDALDH1A1
SCHEMBL14276844 0.78 PIK3CD (0.33) PIK3CDALDH1A1
SCHEMBL13744730 0.78 ALDH1A1 (0.33) PIK3CDALDH1A1
SCHEMBL616629 0.76 SLC6A2 (0.40) PIK3CD
Hydrochloric Acid SCHEMBL618335 0.74 SLC6A2 (0.40) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526239-B1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES OLIPASS CORP (KR) 2021-11-03 EP disclosed
US-11162104-B2 SCN9A antisense pain killer OLIPASS CORPORATION (KR) 2021-11-02 US disclosed
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2019-11-14 US disclosed
US-20190337987-A1 EXON SKIPPING BY PEPTIDE NUCLEIC ACID DERIVATIVES OLIPASS CORPORATION (KR) 2019-11-07 US disclosed
WO-2018069764-A1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2018-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES AR, NR5A1, NR5A2 PIK3CD 3491/4885ALDH1A1 2699/4885TRPM8 625/4885
US-20190337987-A1 EXON SKIPPING BY PEPTIDE NUCLEIC ACID DERIVATIVES PTBP1, RBM17, UPF1 PIK3CD 3828/4885ALDH1A1 4196/4885TRPM8 2144/4885
US-11162104-B2 SCN9A antisense pain killer SCN9A, SCN7A, SCN8A PIK3CD 2715/4885ALDH1A1 3390/4885TRPM8 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.