Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18358719 | 0.84 | PSMB8 (0.44) | PGRALDH1A1MAPTTHRBHPGD | |
| SCHEMBL20656270 | 0.83 | PGR (0.69) | PGRTNKSCYP3A4TNKS2PARP2 | |
| SCHEMBL20079376 | 0.74 | PGR (0.43) | PGRALDH1A1MAPTTHRBHPGD | |
| SCHEMBL20656264 | 0.74 | MAPT (0.61) | PGRALDH1A1MAPTTHRBHPGD | |
| SCHEMBL20079374 | 0.74 | ALDH1A1 (0.55) | PGRALDH1A1MAPTTHRBHPGD | |
| SCHEMBL20656265 | 0.70 | ALDH1A1 (0.43) | PGRALDH1A1MAPTTHRBHPGD | |
| SCHEMBL31473423 | 0.69 | LMNA (0.49) | PGRALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL16883635 | 0.69 | LMNA (0.49) | PGRALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL20079416 | 0.69 | ALDH1A1 (0.42) | PGRALDH1A1MAPTTHRBHPGD | |
| SCHEMBL20079375 | 0.68 | ALDH1A1 (0.51) | PGRALDH1A1MAPTTHRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428049-B2 | TRPA1 modulators | ALGOMEDIX, INC. (US) | 2019-10-01 | — | — | US | disclosed |
| US-9951046-B2 | TRPA1 modulators | ALGOMEDIX, INC. (US) | 2018-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428049-B2 | TRPA1 modulators | TRPA1, TRPV1, TRPV2 | PGR 3776/4885ALDH1A1 1436/4885MAPT 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.