Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783872 | 0.84 | RXRA (0.44) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2008457 | 0.81 | TP53 (0.37) | GAARXFP1KDM4EMEN1KMT2A | |
| SCHEMBL2009099 | 0.78 | NFE2L2 (0.42) | GAAALDH1A1NFE2L2TRPM8 | |
| SCHEMBL783874 | 0.77 | TLR7 (0.42) | ALDH1A1NFE2L2TRPM8 | |
| SCHEMBL2014297 | 0.75 | L3MBTL1 (0.58) | RXFP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2012467 | 0.74 | SCD (0.45) | KDM4EKMT2APOLBNFE2L2 | |
| SCHEMBL2010909 | 0.74 | FFAR1 (0.50) | GAARXFP1KDM4EALDH1A1MEN1 | |
| SCHEMBL12631173 | 0.74 | SCD (0.45) | KDM4EKMT2APOLBNFE2L2 | |
| SCHEMBL11875017 | 0.73 | TP53 (0.47) | RXFP1KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11876582 | 0.72 | BRD4 (0.46) | RXFP1KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011064188-A1 | INSECTICIDAL METHODS USING NITROGEN-CONTAINING HETEROAROMATIC COMPOUNDS | BASF SE (DE) | 2011-06-03 | — | — | WO | disclosed |