Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | PPIA | P62937 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008455 | 0.84 | GAA (0.41) | NFE2L2GAALMNAMAPTTDP1 | |
| SCHEMBL2009099 | 0.80 | NFE2L2 (0.42) | NFE2L2GAAALDH1A1 | |
| SCHEMBL783874 | 0.79 | TLR7 (0.42) | NFE2L2ALDH1A1 | |
| SCHEMBL2012467 | 0.76 | SCD (0.45) | NFE2L2KMT2APOLB | |
| SCHEMBL12631173 | 0.75 | SCD (0.45) | NFE2L2KMT2APOLB | |
| SCHEMBL784068 | 0.74 | RAB9A (0.60) | NPC1RAB9APPIALMNAMAPT | |
| SCHEMBL12631176 | 0.73 | KDM4E (0.46) | NFE2L2ALDH1A1KMT2APOLB | |
| SCHEMBL784516 | 0.73 | RAB9A (0.62) | RXRARXRBRXRGNPC1RAB9A | |
| SCHEMBL30893766 | 0.73 | NPC1 (0.62) | RXRANPC1RAB9APPIAMAPT | |
| SCHEMBL27200112 | 0.73 | NPC1 (0.62) | RXRANPC1RAB9APPIAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071322-A1 | Substituted Pyridopyrazines with a Herbicidal Action | BASF SE (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20110251063-A1 | HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION | BASF SE (DE) | 2011-10-13 | — | — | US | disclosed |
| WO-2011064188-A1 | INSECTICIDAL METHODS USING NITROGEN-CONTAINING HETEROAROMATIC COMPOUNDS | BASF SE (DE) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071322-A1 | Substituted Pyridopyrazines with a Herbicidal Action | PLPBP, PNPO, PFAS | RXRA 2156/4885RXRB 2215/4885RXRG 2231/4885 |
| US-20110251063-A1 | HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION | DDT, KHK, HK1 | RXRA 2254/4885RXRB 2503/4885RXRG 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.