Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | F7 | P08709 | 2/20 | 0.43 |
| ▸ | F3 | P13726 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21052411 | 0.96 | ALDH1A1 (0.49) | ALDH1A1CNR1CNR2CYP3A4ALOX15 | |
| SCHEMBL21052413 | 0.96 | ALDH1A1 (0.49) | ALDH1A1CNR1CNR2CYP3A4ALOX15 | |
| SCHEMBL29119354 | 0.92 | FAAH (0.48) | ALDH1A1CNR1CNR2 | |
| SCHEMBL3688336 | 0.89 | ALDH1A1 (0.55) | ALDH1A1CNR1CNR2CYP3A4ALOX15 | |
| SCHEMBL3688338 | 0.89 | ALDH1A1 (0.55) | ALDH1A1CNR1CNR2CYP3A4ALOX15 | |
| SCHEMBL14695722 | 0.88 | ALDH1A1 (0.51) | ALDH1A1CNR1CNR2CYP3A4ALOX15 | |
| SCHEMBL14695725 | 0.88 | ALDH1A1 (0.51) | ALDH1A1CNR1CNR2CYP3A4ALOX15 | |
| SCHEMBL20086311 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CNR1CNR2CYP3A4ALOX15 | |
| SCHEMBL15726990 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CNR1CNR2CYP3A4ALOX15 | |
| SCHEMBL13065747 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CNR1CNR2CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240325336-A1 | COMBINATION THERAPIES COMPRISING OXYGEN-CONTAINING STRUCTURALLY ENHANCED FATTY ACIDS FOR TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS | NORTHSEA THERAPEUTICS B.V. (NL) | 2024-10-03 | — | — | US | disclosed |
| US-20210177794-A1 | FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS | BASF AS (NO) | 2021-06-17 | — | — | US | disclosed |
| EP-3720431-A1 | FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS | BASF AS (NO) | 2020-10-14 | — | — | EP | disclosed |
| CN-111712240-A | Fatty acid derivatives for the treatment of non-alcoholic steatohepatitis | 巴斯夫股份公司 | 2020-09-25 | — | — | CN | disclosed |
| WO-2019111048-A1 | FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS | BASF AS (NO) | 2019-06-13 | — | — | WO | disclosed |
| US-20180110747-A1 | USE OF THIA OXO COMPOUNDS FOR LOWERING APO C3 | BASF AS (NO) | 2018-04-26 | — | — | US | disclosed |
| US-20180110747-A1 | USE OF THIA OXO COMPOUNDS FOR LOWERING APO C3 | BASF AS (NO) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210177794-A1 | FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS | CPT1A, NR1H3, NR1H2 | ALDH1A1 162/4885CNR1 761/4885CNR2 495/4885 |
| US-20240325336-A1 | COMBINATION THERAPIES COMPRISING OXYGEN-CONTAINING STRUCTURALLY ENHANCED FATTY ACIDS FOR TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS | ACACA, PC, ACACB | ALDH1A1 525/4885CNR1 492/4885CNR2 523/4885 |
| US-20180110747-A1 | USE OF THIA OXO COMPOUNDS FOR LOWERING APO C3 | APOB, TTPA, APOL1 | ALDH1A1 2466/4885CNR1 1419/4885CNR2 2149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.