Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22827652 | 0.87 | TSHR (0.41) | THRBTSHRALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL26294916 | 0.83 | ACHE (0.41) | TSHREPHX1ACHE | |
| SCHEMBL57880 | 0.83 | TSHR (0.52) | THRBTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL16803285 | 0.81 | TSHR (0.50) | THRBTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL11544171 | 0.80 | THRB (0.44) | THRBTSHRALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL890339 | 0.80 | THRB (0.58) | THRBTSHRALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL16367785 | 0.80 | THRB (0.39) | THRBTSHRALDH1A1 | |
| SCHEMBL5884750 | 0.80 | THRB (0.47) | THRBTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL17698929 | 0.79 | TSHR (0.48) | THRBTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL19010218 | 0.79 | ALDH1A1 (0.46) | THRBTSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11786444-B2 | Dental polyfunctional monomers and dental hydroxyl group-containing monomers | MITSUI CHEMICALS, INC. (JP) | 2023-10-17 | — | — | US | disclosed |
| US-20180110683-A1 | DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS | MITSUI CHEMICALS, INC. (JP) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786444-B2 | Dental polyfunctional monomers and dental hydroxyl group-containing monomers | PAM, CAD, FHIT | THRB 873/4885TSHR 2948/4885ALDH1A1 1173/4885 |
| US-20180110683-A1 | DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS | HRH3, HRH1, HRH2 | THRB 639/4885TSHR 861/4885ALDH1A1 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.