SCHEMBL20100394

SCHEMBL20100394

C=C(C)C(=O)N(C(=O)C(C)(C)CC)C1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 7/20 0.33
HSD11B1 P28845 1/20 0.33
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
CCR2 P41597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17888742 0.80 ADH1A (0.35) ADH1CADH1A
SCHEMBL12200780 0.74 ALDH1A1 (0.44) ADH1CADH1ACCR2
SCHEMBL20100390 0.72
SCHEMBL20100433 0.71
SCHEMBL10777585 0.70 L3MBTL1 (0.45) HSD11B1ADH1CADH1A
SCHEMBL18971927 0.70 RIPK1 (0.39) FKBP1AADH1CADH1A
SCHEMBL98826 0.69 TSHR (0.41) HSD11B1ADH1CADH1A
SCHEMBL13713489 0.69 HSD11B1 (0.36) HSD11B1ADH1CADH1A
SCHEMBL12198758 0.68 L3MBTL1 (0.43) HSD11B1ADH1CADH1A
SCHEMBL4085292 0.68 FAAH (0.44) ADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed