SCHEMBL20101404

SCHEMBL20101404

Brc1cccc2c1N=CCC2

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.33
PNMT P11086 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6818612 0.79 TRPA1 (0.35) TRPA1
SCHEMBL10206109 0.76 BCL2L1 (0.39) PNMT
SCHEMBL20825133 0.76 ALDH1A1 (0.42)
SCHEMBL28228041 0.76 ACHE (0.37) PNMT
SCHEMBL18007622 0.73 CA2 (0.41) PNMT
SCHEMBL12961127 0.72 GABRA1 (0.36)
SCHEMBL31061252 0.72 HTR5A (0.41) PNMT
SCHEMBL21696800 0.72 PNMT (0.39) PNMT
SCHEMBL30872001 0.72 ALDH1A1 (0.49) PNMT
SCHEMBL29216432 0.72 ALDH1A1 (0.49) PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3052107-B1 ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS NOVARTIS AG (CH) 2018-05-02 EP disclosed