SCHEMBL20109885

SCHEMBL20109885

CCC1Cc2ccc(OC(C)=O)cc2C1CC

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.48
OPRD1 P41143 2/20 0.46
OPRK1 P41145 1/20 0.46
ACHE P22303 11/20 0.40
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3413664 0.76 MTNR1A (0.44)
SCHEMBL14827326 0.74 OPRM1 (0.55) OPRM1OPRD1OPRK1ACHECA2
SCHEMBL4261860 0.70 MTNR1A (0.62)
SCHEMBL20101858 0.69 OPRM1 (0.51) OPRM1OPRD1OPRK1ACHECA2
SCHEMBL3409346 0.69 OPRM1 (0.46) OPRM1OPRD1OPRK1KDM4ELMNA
SCHEMBL14374374 0.68 ACHE (0.50) OPRM1OPRD1OPRK1ACHECA2
SCHEMBL3407256 0.68 OPRM1 (0.42) OPRM1OPRD1OPRK1KDM4ELMNA
SCHEMBL10585452 0.67 ACHE (0.56) OPRM1OPRD1ACHECA2CA5A
SCHEMBL18976626 0.67 CHRNB2 (0.40)
SCHEMBL11162905 0.66 LMNA (0.49) OPRM1OPRD1OPRK1ACHEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180120701-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, MASK BLANK INCLUDING ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed