SCHEMBL20109989

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20109994	0.99	PLA2G2A (0.40)	CYP1B1CYP1A1CYP1A2PLA2G2APLA2G4A
	SCHEMBL24505859	0.91	CYP1A1 (0.33)	CYP1B1CYP1A1CYP1A2PLA2G2APLA2G4A
	SCHEMBL24178701	0.91	ALOX5 (0.38)	PLA2G2APLA2G4AALOX5PLA2G10CA1
	SCHEMBL18382823	0.90	CYP1A1 (0.33)	CYP1B1CYP1A1CYP1A2PLA2G2APLA2G4A
	SCHEMBL21131913	0.90	ALOX5 (0.37)	CYP1B1CYP1A1CYP1A2PLA2G2APLA2G4A
	SCHEMBL25588897	0.88	ALOX5 (0.41)	CYP1B1CYP1A1CYP1A2PLA2G2APLA2G4A
	SCHEMBL19770494	0.87	ALOX5 (0.51)	CYP1B1CYP1A1CYP1A2PLA2G2APLA2G4A
	SCHEMBL19108528	0.86	PLA2G2A (0.43)	CYP1B1CYP1A1CYP1A2PLA2G2APLA2G4A
	SCHEMBL10122386	0.86	PLA2G2A (0.43)	CYP1B1CYP1A1CYP1A2PLA2G2APLA2G4A
	SCHEMBL17944584	0.86	ALOX5 (0.42)	CYP1B1CYP1A1CYP1A2PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.