Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109406 | 0.89 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL20100735 | 0.85 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL20104860 | 0.83 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL20104863 | 0.77 | KMT2A (0.40) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL20100739 | 0.72 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL20104861 | 0.71 | PTGS2 (0.36) | ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8298120 | 0.70 | FAAH (0.59) | ALDH1A1SMN1; SMN2MAPTKMT2AFAAH | |
| SCHEMBL20729541 | 0.69 | KMT2A (0.42) | ALDH1A1SMN1; SMN2LMNAKMT2AFAAH | |
| SCHEMBL24115710 | 0.68 | CA1 (0.44) | ALDH1A1SMN1; SMN2KMT2AFAAHMEN1 | |
| SCHEMBL20100738 | 0.68 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118676-A1 | NITRIC OXIDE DONATING DERIVATIVES OF LATANOPROST FREE ACID | NICOX S.A. (FR) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118676-A1 | NITRIC OXIDE DONATING DERIVATIVES OF LATANOPROST FREE ACID | PTGIS, NOS2, NOS1 | ALDH1A1 665/4885SMN1; SMN2 4557/4885LMNA 2439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.