SCHEMBL20115466

SCHEMBL20115466

Bc1c(B)c(B)c(-c2c3ccccc3c(-c3cccc4oc5ccc(-c6ccc(-c7ccccc7)cc6)cc5c34)c3ccccc23)c(B)c1B

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 5/20 0.42
PLA2G4A P47712 5/20 0.42
PLA2G10 O15496 1/20 0.40
PRKDC P78527 3/20 0.35
WEE1 P30291 1/20 0.34
ALOX5 P09917 1/20 0.34
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
PIM1 P11309 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
NPC1 O15118 3/20 0.33
HPGD P15428 3/20 0.33
RAB9A P51151 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26049678 1.00 PLA2G2A (0.42) PLA2G2APLA2G4APLA2G10PRKDCWEE1
SCHEMBL25631795 0.94 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10PRKDCALOX5
SCHEMBL25631768 0.94 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10PRKDCALOX5
SCHEMBL25744488 0.94 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10WEE1ALOX5
SCHEMBL24505852 0.90 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10PRKDCWEE1
SCHEMBL22130579 0.90 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10WEE1ALOX5
SCHEMBL19784416 0.90 MMP12 (0.35) PLA2G2APLA2G4APLA2G10PRKDCALOX5
SCHEMBL24653306 0.90 ALOX5 (0.35) PLA2G2APLA2G4APLA2G10WEE1ALOX5
SCHEMBL24505789 0.89 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10PRKDCWEE1
SCHEMBL26404245 0.89 PLA2G2A (0.48) PLA2G2APLA2G4APLA2G10PRKDCWEE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371376-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME SFC CO., LTD. (KR) 2023-11-16 US disclosed
EP-4254526-A1 ORGANIC LIGHT-EMITTING DEVICE COMPRISING NOVEL ORGANIC COMPOUND IN EMISSION LAYER SFC Co., Ltd. (KR) 2023-10-04 EP disclosed
US-10693084-B2 Compound for organic light-emitting device and organic light-emitting device including same SFC CO., LTD. (KR) 2020-06-23 US disclosed
US-20180123055-A1 COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME SFC CO., LTD. (KR) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10693084-B2 Compound for organic light-emitting device and organic light-emitting device including same CYP1B1, CYP1A1, CRY2 PLA2G2A 1057/4885PLA2G4A 1308/4885PLA2G10 1475/4885
US-20230371376-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME PPOX, MAP1LC3A, VDAC2 PLA2G2A 1893/4885PLA2G4A 1054/4885PLA2G10 857/4885
US-20180123055-A1 COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME CYP1B1, CYP1A1, CRY2 PLA2G2A 1057/4885PLA2G4A 1308/4885PLA2G10 1475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.