Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23661902 | 0.82 | CYP11B1 (0.44) | TSHRESR1ESR2CYP1A2CYP3A4 | |
| SCHEMBL18427303 | 0.82 | KCNA5 (0.39) | MEN1ALDH1A1KMT2ASMN1; SMN2CHRM2 | |
| SCHEMBL18598771 | 0.81 | KCNH2 (0.37) | CHRM2CHRM1TSHRESR1ESR2 | |
| SCHEMBL18811782 | 0.81 | ESR1 (0.37) | ALDH1A1SMN1; SMN2CHRM2TSHRESR1 | |
| SCHEMBL21012176 | 0.78 | CYP1A2 (0.39) | MEN1ALDH1A1KMT2ATSHRESR1 | |
| SCHEMBL21675851 | 0.76 | SLC6A4 (0.31) | ESR1ESR2MAOASLC6A2SLC6A4 | |
| SCHEMBL22426189 | 0.75 | CYP1A2 (0.37) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3249970 | 0.74 | MAOA (0.50) | ALDH1A1MAPTSMN1; SMN2CHRM2TSHR | |
| SCHEMBL21085218 | 0.72 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2TSHRNPC1ESR1 | |
| SCHEMBL25003875 | 0.70 | TSHR (0.41) | MEN1KMT2ASMN1; SMN2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308617-B2 | Triazole benzamide derivatives and the compositions and methods of treatment regarding the same | An2H Discovery Limited (IE) | 2019-06-04 | — | — | US | disclosed |
| US-20180118697-A1 | TRIAZOLE BENZAMIDE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME | NYSNOBIO IRELAND DAC (IE) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118697-A1 | TRIAZOLE BENZAMIDE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME | PINK1, ATG7, ADRM1 | PCSK9 4304/4885MEN1 3909/4885ALDH1A1 504/4885 |
| US-10308617-B2 | Triazole benzamide derivatives and the compositions and methods of treatment regarding the same | PINK1, ATG7, ADRM1 | PCSK9 4304/4885MEN1 3909/4885ALDH1A1 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.