Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118169 | 0.87 | P2RX7 (0.35) | OPRM1OPRK1OPRL1P2RX7HSD11B1 | |
| SCHEMBL20118172 | 0.87 | P2RX7 (0.35) | OPRM1OPRK1OPRL1P2RX7HSD11B1 | |
| SCHEMBL20118401 | 0.85 | PSEN1 (0.37) | OPRM1OPRK1OPRL1P2RX7MEN1 | |
| SCHEMBL20118049 | 0.84 | CASP6 (0.36) | OPRM1OPRK1OPRL1P2RX7MEN1 | |
| SCHEMBL20118395 | 0.81 | KMT2A (0.39) | P2RX7MEN1GAACASP6KMT2A | |
| SCHEMBL20118397 | 0.81 | P2RX7 (0.35) | P2RX7MEN1GAACASP6KMT2A | |
| SCHEMBL20118389 | 0.76 | GRM5 (0.33) | OPRM1OPRK1OPRL1P2RX7ALDH1A1 | |
| SCHEMBL20118222 | 0.76 | OPRL1 (0.34) | OPRM1OPRK1OPRL1P2RX7MEN1 | |
| SCHEMBL20118223 | 0.76 | GRM5 (0.33) | OPRM1OPRK1OPRL1P2RX7ALDH1A1 | |
| SCHEMBL20118174 | 0.75 | CRHR1 (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |