Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.35 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118185 | 0.81 | OPRM1 (0.35) | P2RX7MEN1GAACASP6KMT2A | |
| SCHEMBL20118172 | 0.77 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL20118169 | 0.77 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL20118401 | 0.76 | PSEN1 (0.37) | P2RX7MEN1GAACASP6KMT2A | |
| SCHEMBL20118395 | 0.72 | KMT2A (0.39) | P2RX7MEN1GAACASP6KMT2A | |
| SCHEMBL20118049 | 0.68 | CASP6 (0.36) | P2RX7MEN1GAACASP6KMT2A | |
| SCHEMBL20118223 | 0.68 | GRM5 (0.33) | P2RX7 | |
| SCHEMBL20118389 | 0.68 | GRM5 (0.33) | P2RX7 | |
| SCHEMBL20118222 | 0.68 | OPRL1 (0.34) | P2RX7MEN1GAACASP6KMT2A | |
| SCHEMBL20118221 | 0.68 | MAPK13 (0.38) | P2RX7MEN1GAACASP6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |