Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20015251 | 0.84 | NOTUM (0.36) | NOTUMPTGS2 | |
| SCHEMBL20123682 | 0.84 | ALDH1A1 (0.37) | NOTUMALDH1A1L3MBTL1 | |
| SCHEMBL20123649 | 0.78 | ACHE (0.35) | NOTUM | |
| SCHEMBL21183818 | 0.78 | NOTUM (0.33) | NOTUM | |
| SCHEMBL20014575 | 0.78 | ADRA2A (0.33) | NOTUM | |
| SCHEMBL20123771 | 0.78 | TEAD1 (0.33) | NOTUMALDH1A1L3MBTL1PTGS2 | |
| SCHEMBL20014966 | 0.75 | NOTUM (0.40) | NOTUM | |
| SCHEMBL20123623 | 0.74 | NOTUM (0.42) | NOTUM | |
| SCHEMBL20123590 | 0.72 | DRD2 (0.32) | NOTUM | |
| SCHEMBL20123727 | 0.72 | ACHE (0.35) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |